Racemic 4-(4-tert-butylphenyl)-2,6-dimethylcyclohex-3-enecarboxylic acid
نویسندگان
چکیده
The chirality of the title compound, C(19)H(26)O(2), is solely generated by the presence of the double bond in the cyclo-hexene ring. This compound was synthesized to study the inter-action of the two enanti-omers in the solid state. The resultant racemate is made up of carboxylic acid RS dimers. Inter-molecular O-H⋯O hydrogen bonds produce centrosymmetric R(2) (2)(8) rings which dimerize the two chiral enanti-omers through their carboxyl groups.
منابع مشابه
4-(3-Methoxyphenyl)-2,6-dimethylcyclohex-3-enecarboxylic acid
The racemic title compound, C(16)H(20)O(3), was synthesized to study the hydrogen-bonding inter-action of the two enanti-o-mers in the solid state. In the crystal structure, R and S pairs of the racemate are linked by pairs of inter-molecular O-H⋯O hydrogen bonds, producing centrosymmetric R(2) (2)(8) rings.
متن کاملSynthesis of a 6-aryloxymethyl-5-hydroxy-2,3,4,5-tetrahydro-[1H]-2-benzazepin-4-one: a muscarinic (M3) antagonist.
A synthesis of the racemic 6-aryloxymethyl-5-hydroxy-2,3,4,5-[1H]-2-tetrahydrobenzazepin-4-one , for evaluation as a muscarinic (M(3)) antagonist, is described. 2-[2-tert-Butyldimethylsilyloxymethyl-6-(2,6-dimethoxyphenoxymethyl)phenyl]propan-2-ol was prepared from 2,6-dimethyl-1-bromobenzene and taken through to N-[3-(2,6-dimethoxyphenoxymethyl)-2-(propen-2-yl)phenyl]methyl-N-prop-2-enyl 2-nit...
متن کاملrac-4-(2-Methoxyphenyl)-2,6-dimethylcyclohex-3-enecarboxylic acid
The title compound, C(16)H(20)O(3), was synthesized to study the hydrogen-bonding inter-actions of the two enanti-omers in the solid state. Inter-molecular O-H⋯O hydrogen bonds produce centrosymmetric R(2) (2)(8) rings which dimerize the two chiral enanti-omers together through their carboxyl groups.
متن کامل1,1′-Bis[bis(4-tert-butylphenyl)methyl]ferrocene
The molecule of the title compound, [Fe(C26H31)2], is located on an inversion center. The two cyclopentadienyl rings exhibit a staggered conformation, which results from the bulky bis(4-tert-butylphenyl)methyl substituents situated on opposite sides of the molecule.
متن کاملNovel C-3 cyclic ether cephalosporins and their orally absorbed prodrug esters.
modified form, the Wittig cyclisation chemistry of Woodwardet al.3) and Nayler et al.4) (Scheme 1). The racemic acids (4) were converted in conventional fashion into the corresponding chloromethyl ketones (5), which were then used to alkylate the azetidinone thiol5) (6). Addition of ^-butyl glyoxylate to the derived ketone (7), followed by elaboration of the aminols (8) with thionyl chloride an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 64 شماره
صفحات -
تاریخ انتشار 2008